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Markus Fendt Selected Research

Orexins

1/2022Orexin deficiency affects sensorimotor gating and its amphetamine-induced impairment.
1/2021Orexin deficiency affects sociability and the acquisition, expression, and extinction of conditioned social fear.
1/2017Increased anxiety but normal fear and safety learning in orexin-deficient mice.
3/2014Behavioral analysis of narcoleptic episodes in orexin-deficient mice.
12/2012The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors.
9/2011Narcoleptic episodes in orexin-deficient mice are increased by both attractive and aversive odors.

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Markus Fendt Research Topics

Disease

8Anxiety Disorders (Anxiety Disorder)
05/2021 - 01/2020
6Narcolepsy
01/2017 - 09/2011
4Cataplexy
01/2017 - 09/2011
4Sleep Initiation and Maintenance Disorders (Insomnia)
10/2015 - 01/2013
3Mental Disorders (Mental Disorder)
05/2021 - 01/2020
2Schizophrenia (Dementia Praecox)
01/2022 - 01/2021
2Sleep Wake Disorders
10/2013 - 01/2013
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2022
1Wounds and Injuries (Trauma)
01/2021
1Central Nervous System Infections (Central Nervous System Infection)
09/2020
1Gliosis
01/2017
1Disorders of Excessive Somnolence (Hypersomnia)
01/2017
1Alzheimer Disease (Alzheimer's Disease)
01/2017
1Memory Disorders (Memory Loss)
01/2017
1Neuroinflammatory Diseases
01/2017
1Phobic Disorders (Phobia)
01/2016
1Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
01/2016
1Epilepsy (Aura)
10/2015
1Psychotic Disorders (Schizoaffective Disorder)
10/2015
1Inflammation (Inflammations)
10/2015
1Pain (Aches)
10/2015
1Parkinson Disease (Parkinson's Disease)
11/2011
1Shock
02/2004

Drug/Important Bio-Agent (IBA)

6OrexinsIBA
01/2022 - 09/2011
3almorexantIBA
10/2013 - 12/2012
2NeuropeptidesIBA
01/2020 - 01/2020
2Orexin Receptor AntagonistsIBA
10/2013 - 01/2013
2suvorexantIBA
10/2013 - 01/2013
2Orexin ReceptorsIBA
10/2013 - 01/2013
1Oxytocin (Pitocin)FDA LinkGeneric
05/2021
1Biomarkers (Surrogate Marker)IBA
01/2021
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2021
1Viral RNAIBA
09/2020
1human neuropeptide SIBA
01/2020
1Hormones (Hormone)IBA
01/2020
1methysticinIBA
01/2017
1CytokinesIBA
01/2017
1Interleukin-17 (Interleukin 17)IBA
01/2017
1Antidepressive Agents (Antidepressants)IBA
01/2016
1Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2016
1Complement System Proteins (Complement)IBA
01/2016
1Serotonin (5 Hydroxytryptamine)IBA
01/2016
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
01/2015
1Modafinil (Provigil)FDA Link
01/2015
1Pharmaceutical PreparationsIBA
08/2014
1ErgolinesIBA
08/2014
1Histamine H3 Receptors (Histamine H3 Receptor)IBA
08/2014
1MK-6096IBA
01/2013
1N- ((1- ((5- (4- fluorophenyl)- 2- methyl- 4- thiazolyl)carbonyl)- 2- piperidinyl)methyl)- 4- benzofurancarboxamideIBA
01/2013
1SynucleinsIBA
11/2011
1Dopamine (Intropin)FDA LinkGeneric
11/2011
1MuscimolIBA
02/2004

Therapy/Procedure

4Therapeutics
05/2021 - 01/2020
1Oral Administration
01/2017
1Traditional Medicine (Folk Remedies)
10/2015
1Injections
02/2004